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Appendix G: Pesticide Groups Based on Sites of Action

Author: OMAFRA Staff
Creation Date: 28 July 2007
Last Reviewed: 15 June 2009
Pub 812: Field Crop Protection Guide > Chapter 10: Appendices > Appendix G: Pesticide Groups Based on sites of Action

Excerpt from Chapter 10, Field Crop Protection Guide, Order this publication

  1. Insecticides
  2. Fungicides

Insecticides

The classification scheme listed below is adapted from the Insecticide Action Committee Mode of Action Classification (IRAC) V5.2, September 2006.

Group #Primary Site of ActionGroup NameProduct Name (s)Risk of Developing Resistance
1A1Acetylcholine esterase inhibitorscarbamateFuradan 480 F, Lannate, Pirimor 50 DF, Sevin XLR, Vydate L
High
1B organophosphateAgrox B-2, Agrox CD, Counter 15 G, Cygon 480, Imidan 50 WP, Lagon 480, Lorsban 4E, Lorsban 15 G, Malathion 500 E, Monitor 480, Pyrifos 15 G, Pyrifos 50 W, Pyrinex 480 EC, Thimet 15 G
High
2AGABA-gated chloride channel agonistschlorinated cyclodieneThiodan 4 EC, Thiodan 50 WP, Thionex 50 W
Moderate
3Sodium channel modulatorsdiphenylethaneKelthane 50 W
High
pyrethroidDecis 5 EC, Force 3.0 G, Matador 120 EC, Pounce 384 EC, Ripcord 400 EC
4Nicotinic acetylcholine receptor agonistsneonicotinoidsAdmire, Gaucho 480 FL, Gaucho GS, Poncho 600, Cruiser 5FS, Cruiser 350FS, Helix Xtra, Prosper
Low to Moderate
5Nicotinic acetylcholine receptor agonists (allosteric, not group 4)naturalyte/spinosynsSuccess 480 SC, Delegate
Low
9BCompounds of unknown or non-specific mode of action (selective feeding blockers)pyridinesFulfill 50 WG
Low
11Microbial disruptors of insect midgut membranesbiologicalsBioprotec CAF, Dipex 2X DF, Novodor, Thurcide HPS
Low
17Chitin biosynthesis inhibitor (Diperta only) cyromazineCitation 75 WP, Governor 75 WP
Low
21Mitochondrial complex I electron transport inhibitorbotanicalsRotenone 5, Rotenone 1% WP, Rotenone 5% WP
Low
24Mitochondrial complex IV electron transport inhibitorsinorganicsAluminum phosphide 

1 Although sharing the same primary target site, it is possible that not all members of a single major mode of action (MoA) class have been shown to be cross-resistant . However, for the purposes of this classification system, it should be assumed that cross-resistance exists between compounds in any one sub-group.

Fungicides

This classification scheme is based on the Fungicide Resistance Action Committee (FRAC) List, 2006

Group #Primary Site of ActionGroup NameProduct Name (s)Risk of Developing Resistance
1Inhibition of mitosis (turbulin formation)methyl-benzimidazole carbamatesDCT, Senator 70 WP
High
2Affect cell division, DNA & RNA synthesis & metabolismdicarboximide Ronilan EG, Rovral WP
Moderate to High
3DMI (Demethylation Inhibitor): Inhibition of sterol synthesistriazoleBaytan 30, Bumper 418 EC, Dividend XL RTA, Folicur 432F, Gemini, Quilt, Stratego, Tilt 250 E, Raxil T, Topas 250 E, Helix Xtra
Moderate
4Phenylamides Affect RNA synthesisacylamine (phenylamides)Allegiance FL, Apron FL, Apron XL LS Apron Maxx, Helix Xtra, Prosper
High
52Inhibition of an isomerase in sterol biosynthesismorpholinesAcrobat MZ
Low to Moderate
7Fungal respirationcarboxamide anilideAnchor, Lance WDG, Vitaflo 280, Vitavax RS, Gaucho CS, Prosper
Moderate
11Fungal respiration: Quinone Outside Inhibitors (QOI)strobilurinCabrio EG, Dynasty 100, Headline EC, Quadris, Quilt, Stratego 250EC, Reason 500 SC, Tanos 50 DF
High
12Osmotic signal tansductionphenylpyrrolesMaxim 480 FS, Apron Maxx, Helix Xtra
Low to Mod
14Lipid peroxidation (proposed)aromatic hydrocarbon chlorophenylBotran 75 W, Quintozene 75 WP
Low to Moderate
22Mitosis and cell divisionbenzamideGavel 75 DF
Low to Moderate
25Protein synthesisantibioticStreptomycin
High
27Unknowncyanoacetamide oxime (acetamide)Curzate 60 DF
Low to Moderate
28Cell membrane permeability (proposed)carbamateTatoo C
Low to Moderate
33UnknownphosphonateAliette WDG
Low
M1Multi-site, contactinorganicCopper Spray, Copper 53 W, Kocide 101 WP, Kocide DF, Microscopic Sulphur, Oxidate, Parasol WP
Low
M2Multi-site, contactdithiocarbamateAnchor, Acrobat MZ, Dithane, Dithane F 45, Ferbam 76 WDG, Gavel 75 DF, Manzate DF, Penncozeb 80, Polyram DF, Ridomil Gold, Thiram 75 WP, Vitaflo 280, Vitavax RS, Zineb 80 W, Gaucho CS, Prosper, Gemini
Low
M3Multi-site, contactphthalimideAgrox B-2, Agrox CD, Captan, DCT, Maestro 75 DF, Supra Captan 80 WDG
Low
M4Multi-site, contactchloronitrileBravo 500, Tatoo C
Low

2 Depending on the reference sources, the cinnamic acid group may be listed as a group 5 or group 15.

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